To date, datasets have been released for cells treated with a broad range of perturbations, including siRNA and CRISPR/Cas9 genetic knockdown/knockout, small molecules at multiple concentrations, SARS-CoV-2 virus, immune-focused proteins, and a model of COVID-19 cytokine storm.

Release Date
June 2019
August 2020
April 2020
August 2020
January 2023
Cell Types
HUVEC
RPE
U2OS
HepG2
HUVEC
HRCE
Vero
HUVEC
HUVEC
Stains (Channels)
Hoechst
ConA
Phalloidin
Syto14
MitoTracker
WGA
Hoechst
ConA
Phalloidin
Syto14
MitoTracker
WGA
Hoechst
ConA
Phalloidin
Syto14
WGA
Hoechst
ConA
Phalloidin
Syto14
MitoTracker
WGA
Hoechst
ConA
Phalloidin
Syto14
MitoTracker
WGA
Plate Density
384-well
1536-well
1536-well
1536-well
1536-well
Imaging Sites per Well
2
4
4
1
1
Perturbations Evaluated
1,138 siRNAs
434 soluble factors at 6 concentrations
1,672 small molecules at 6+ concentrations
Three viral conditions (active virus, irradiated, mock)
1,856 small molecules at 4-6 concentrations in three COVID-19-associated cytokine storm conditions (severe storm, healthy, and no cytokines)
17,063 CRISPR/Cas9-mediated gene knockouts
1,674 compounds at 8 concentrations each
Total Number of Images
125,510
131,953
305,520
70,384
~2.2M
Image Dimension
512x512x6
1024x1024x6
1024x1024x5
2048x2048x6
2048x2048x6
Compressed Dataset Size
~46GB
~185GB
~450GB
~409GB
~83,100GB
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